I Am new to Omsi2 and love the sim its great only thing is I Cant pick passengers up as the destinations will not let me program them to the university or anywhere elts here is a picture to more explain what I Mean
With regards to your issue, you will need to install the correct .hof file for each map into your bus' directory (where the .bus file is located). You can find the .hof file for Coterell in the download. All you need to do is move that file over into the bus directory of the E200 and you're sorted.
Then, you just need to select Coterell as your depot when you spawn the bus. The destinations should then show up.